2xfz Summary

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Structure of cytotoxic domain of colicin E3 bound to the 70S ribosome

The structure was published by Ng, C.L., Lang, K., Meenan, N.A.G., et al., Kelley, A.C., Kleanthous, C., and Ramakrishnan, V., in 2010 in a paper entitled "Structural Basis for 16S Ribosomal RNA Cleavage by the Cytotoxic Domain of Colicin E3." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 3.2 Å and deposited in 2010.

The experimental data on which the structure is based was also deposited.

This entry contains 1191 copies of 24 unique biopolymers (complete list).

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The most likely quaternary structure is a 25meric assembly.


The are more than 5 unique protein polymers in this entry. More information is available on the Uniprot cross references page.

This entry contains 21 unique UniProt proteins:

UniProt accession Name Organism PDB
P80371 (1 - 256) 30S RIBOSOMAL PROTEIN S2 Thermus thermophilus HB8
P80372 (1 - 239) 30S RIBOSOMAL PROTEIN S3 Thermus thermophilus HB8
P80373 (1 - 209) 30S RIBOSOMAL PROTEIN S4 Thermus thermophilus HB8
Q5SHQ5 (1 - 162) 30S RIBOSOMAL PROTEIN S5 Thermus thermophilus HB8
Q5SLP8 (1 - 101) 30S RIBOSOMAL PROTEIN S6 Thermus thermophilus HB8
P17291 (1 - 156) 30S RIBOSOMAL PROTEIN S7 Thermus thermophilus HB8
Q5SHQ2 (1 - 138) 30S RIBOSOMAL PROTEIN S8 Thermus thermophilus HB8
P80374 (1 - 128) 30S RIBOSOMAL PROTEIN S9 Thermus thermophilus HB8
Q5SHN7 (1 - 105) 30S RIBOSOMAL PROTEIN S10 Thermus thermophilus HB8
P80376 (1 - 129) 30S RIBOSOMAL PROTEIN S11 Thermus thermophilus HB8
Q5SHN3 (2 - 132) 30S RIBOSOMAL PROTEIN S12 Thermus thermophilus HB8
P80377 (1 - 126) 30S RIBOSOMAL PROTEIN S13 Thermus thermophilus HB8
Q5SHQ1 (1 - 61) 30S RIBOSOMAL PROTEIN S14 TYPE Z Thermus thermophilus HB8
Q5SJ76 (1 - 89) 30S RIBOSOMAL PROTEIN S15 Thermus thermophilus HB8
Q5SJH3 (1 - 88) 30S RIBOSOMAL PROTEIN S16 Thermus thermophilus HB8
Q5SHP7 (1 - 105) 30S RIBOSOMAL PROTEIN S17 Thermus thermophilus HB8
Q5SLQ0 (1 - 88) 30S RIBOSOMAL PROTEIN S18 Thermus thermophilus HB8
Q5SHP2 (1 - 93) 30S RIBOSOMAL PROTEIN S19 Thermus thermophilus HB8
P80380 (1 - 106) 30S RIBOSOMAL PROTEIN S20 Thermus thermophilus HB8
Q5SIH3 (1 - 27) 30S RIBOSOMAL PROTEIN THX Thermus thermophilus HB8
P00646 (455 - 512) COLICIN-E3 Escherichia coli

For more information on cross references to other databases click Cross references in the menu on the left.