2xcy Summary

pdbe.org/2xcy
spacer

CRYSTAL STRUCTURE OF ASPERGILLUS FUMIGATUS SIALIDASE

The structure was published by Telford, J.C., Yeung, J.H., Xu, G., et al., Bennet, A.J., Moore, M.M., and Taylor, G.L., in 2011 in a paper entitled "The Aspergillus Fumigatus Sialidase is a Kdnase: Structural and Mechanistic Insights." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.84 Å and deposited in 2010.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of EXTRACELLULAR SIALIDASE/NEURAMINIDASE, PUTATIVE.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A EXTRACELLULAR SIALIDASE/NEURAMINIDASE, PUTATIVE Q4WQS0 (21-406) (SIA_ASPFU)search Aspergillus fumigatus Af293search 100% 386 100%
B EXTRACELLULAR SIALIDASE/NEURAMINIDASE, PUTATIVE Q4WQS0 (21-406) (SIA_ASPFU)search Aspergillus fumigatus Af293search 100% 386 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q4WQS0 (21 - 406) EXTRACELLULAR SIALIDASE/NEURAMINIDASE, PUTATIVE Aspergillus fumigatus

Chain Sequence family (Pfam)
A, B (Q4WQS0) PF13088: BNR repeat-like domainsearch

Chain ID Biological process (GO) Molecular function (GO) Cellular component (GO)
A, B (Q4WQS0) biological_processsearch carbohydrate metabolic processsearch metabolic processsearch exo-alpha-(2->6)-sialidase activitysearch exo-alpha-sialidase activitysearch exo-alpha-(2->3)-sialidase activitysearch exo-alpha-(2->8)-sialidase activitysearch hydrolase activity, acting on glycosyl bondssearch hydrolase activitysearch cellular_componentsearch

Chain InterPro annotation
A, B Sialidasessearch Sialidase familysearch