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Crystal structure of Aspergillus fumigatus sialidase

X-ray diffraction
1.84Å resolution
PDB entry 2xcy coloured by chain, front view.
PDB entry 2xcy coloured by chain, side view.
PDB entry 2xcy coloured by chain, top view.
Source organism: Aspergillus fumigatus
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Exo-alpha-sialidase
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Multimeric state: monomeric
PDBe Complex ID: PDB-CPX-175839
Assembly 2
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Assembly Name: Exo-alpha-sialidase
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Multimeric state: monomeric
PDBe Complex ID: PDB-CPX-175839

Macromolecules

Exo-alpha-sialidase
Chains: A, B
Length: 386 amino acids
Theoretical weight: 42.35 KDa
Source organism: Aspergillus fumigatus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q4WQS0 (Residues: 21-406; Coverage: 100%)
Gene name: AFUA_4G13800
Pfam: BNR repeat-like domain
InterPro:
CATH: Neuraminidase
Exo-alpha-sialidase in PDB entry 2xcy, assembly 1, front view.
Exo-alpha-sialidase in PDB entry 2xcy, assembly 1, side view.
Exo-alpha-sialidase in PDB entry 2xcy, assembly 1, top view.
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