2x7g Summary

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STRUCTURE OF HUMAN SERINE-ARGININE-RICH PROTEIN-SPECIFIC KINASE 2 (SRPK2) BOUND TO PURVALANOL B

A publication describing this structure is not available. The depositing authors are Pike, A.C.W.search; Savitsky, P.search; Fedorov, O.search; Krojer, T.search; Ugochukwu, E.search; Von Delft, F.search; Gileadi, O.search; Edwards, A.search; Arrowsmith, C.H.search; Weigelt, J.search; Bountra, C.search; Knapp, S.search

This crystal structure was determined using X-ray diffraction at a resolution of 2.5 Å and deposited in 2010.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of UNCHARACTERIZED PROTEIN SRPK2.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A UNCHARACTERIZED PROTEIN SRPK2 P78362 (51-688) (SRPK2_HUMAN)search Homo sapienssearch < 90% 389 88%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P78362 (51 - 688) UNCHARACTERIZED PROTEIN SRPK2 Homo sapiens

Chain Structural classification (CATH) Sequence family (Pfam)
A Phosphorylase Kinase; domain 1search, Transferase(Phosphotransferase) domain 1search Protein kinase domainsearch

Chain ID Molecular function (GO) Biological process (GO)
A (P78362) ATP bindingsearch protein kinase activitysearch protein serine/threonine kinase activitysearch transferase activity, transferring phosphorus-containing groupssearch protein phosphorylationsearch

Chain InterPro annotation
A Protein kinase domainsearch Serine/threonine-protein kinase, active sitesearch Protein kinase-like domainsearch Protein kinase, ATP binding sitesearch