› 2x3l

X-ray diffraction
2Å resolution

Crystal Structure of the Orn_Lys_Arg decarboxylase family protein SAR0482 from Methicillin-resistant Staphylococcus aureus

Released:
DOI: 10.2210/pdb2x3l/pdb
PDB entry 2x3l coloured by chain, front view.
PDB entry 2x3l coloured by chain, side view.
PDB entry 2x3l coloured by chain, top view.
Source organism: Staphylococcus aureus
Primary publication:
The Scottish Structural Proteomics Facility: targets, methods and outputs.
Oke M, Carter LG, Johnson KA, Liu H, McMahon SA, Yan X, Kerou M, Weikart ND, Kadi N, Sheikh MA, Schmelz S, Dorward M, Zawadzki M, Cozens C, Falconer H, Powers H, Overton IM, van Niekerk CA, Peng X, Patel P, Garrett RA, Prangishvili D, Botting CH, Coote PJ, Dryden DT, Barton GJ, Schwarz-Linek U, Challis GL, Taylor GL, White MF, Naismith JH
J Struct Funct Genomics 11 167-80 (2010)
PMID: 20419351

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-163304 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ORN/LYS/ARG DECARBOXYLASE FAMILY PROTEIN Chains: A, B
Molecule details ›
Chains: A, B
Length: 446 amino acids
Theoretical weight: 51.12 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand PLP 2 x PLP
Ligand SM 7 x SM
Ligand EDO 1 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-3
Spacegroup: P21
Unit cell:
a: 50.677Å b: 137.283Å c: 62.258Å
α: 90° β: 109.64° γ: 90°
R-values:
R R work R free
0.231 0.229 0.277
Expression system: Escherichia coli

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Citations

10 review citations

Genomics of bacterial and archaeal viruses: dynamics within the prokaryotic virosphere.
Krupovic et al. (2011)
9 more

2 mentions without citation

A Survey of Pyridoxal 5'-Phosphate-Dependent Proteins in the Gram-Positive Model Bacterium Bacillus subtilis.
Richts et al. (2019)
1 more