AURORA-A INHIBITOR STRUCTURE (2ND CRYSTAL FORM)
The structure was published by Dodson, C.A., Kosmopoulou, M., Richards, M.W., et al., Bavetsias, V., Blagg, J., and Bayliss, R., in 2010 in a paper entitled "Crystal Structure of an Aurora-A Mutant that Mimics Aurora-B Bound to Mln8054: Insights Into Selectivity and Drug Design." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 3.302 Å and deposited in 2009.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of SERINE/THREONINE-PROTEIN KINASE 6 AURORA/IPL1-RELATED KINASE 1, BREAST TUMOR-AMPLIFIED KINASE, AURORA-A, AURORA-RELATED KINASE 1, HARK1.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: