› 2wnp

X-ray diffraction
1.21Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-126363 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ficolin-1 Chain: F
Molecule details ›
Chain: F
Length: 217 amino acids
Theoretical weight: 24.23 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: O00602 (Residues: 110-326; Coverage: 73%)
Gene names: FCN1, FCNM
Sequence domains: Fibrinogen beta and gamma chains, C-terminal globular domain
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand CA 1 x CA
Ligand IPA 1 x IPA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM30A
Spacegroup: R3
Unit cell:
a: 73.55Å b: 73.55Å c: 124.76Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.178 0.178 0.191
Expression system: Spodoptera frugiperda

Quick links

Citations

23 review citations

Biological roles of glycans.
Varki A. (2017)
22 more

2 mentions without citation

Carbohydrate recognition properties of human ficolins: glycan array screening reveals the sialic acid binding specificity of M-ficolin.
Gout et al. (2010)
1 more