› 2wj8

X-ray diffraction
3.29Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
hetero icosamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136970 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
Nucleoprotein Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T
Length: 391 amino acids
Theoretical weight: 43.51 KDa
Source organism: Human respiratory syncytial virus A strain Long
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P03418 (Residues: 1-391; Coverage: 100%)
Gene name: N
Sequence domains: Pneumovirus nucleocapsid protein
RNA (5'-R(*CP*CP*CP*CP*CP*C)-3') Chains: a, b, c, d, e, f, g, h, i, j, k, l, m, n, o, p, q, r, s, t
Molecule details ›
Chains: a, b, c, d, e, f, g, h, i, j, k, l, m, n, o, p, q, r, s, t
Length: 7 nucleotides
Theoretical weight: 2.09 KDa
Source organism: Escherichia coli BL21(DE3)

Ligands and Environments

1 bound ligand:
Ligand BO4 12 x BO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: C2
Unit cell:
a: 218.2Å b: 220.99Å c: 218.1Å
α: 90° β: 93.09° γ: 90°
R-values:
R R work R free
0.206 0.205 0.226
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

53 review citations

Progress in understanding and controlling respiratory syncytial virus: still crazy after all these years.
Collins et al. (2011)
52 more

32 mentions without citation

Nucleic acid packaging in viruses.
Speir et al. (2012)
31 more