2wj8 Summary

pdbe.org/2wj8
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Respiratory Syncitial Virus RiboNucleoProtein

The structure was published by Tawar, R.G., Duquerroy, S., Vonrhein, C., et al., Bhella, D., Eleouet, J., and Rey, F.A., in 2009 in a paper entitled "Crystal Structure of a Nucleocapsid-Like Nucleoprotein-RNA Complex of Respiratory Syncytial Virus" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 3.29 Å and deposited in 2009.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely NUCLEOPROTEIN and RNA (5'-R(*CP*CP*CP*CP*CP*C)-3').

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A NUCLEOPROTEIN P03418 (1-391) (NCAP_HRSVA)search Human respiratory syncytial virus A2search 96% 391 96%
B NUCLEOPROTEIN P03418 (1-391) (NCAP_HRSVA)search Human respiratory syncytial virus A2search 96% 391 96%
C NUCLEOPROTEIN P03418 (1-391) (NCAP_HRSVA)search Human respiratory syncytial virus A2search 96% 391 96%
D NUCLEOPROTEIN P03418 (1-391) (NCAP_HRSVA)search Human respiratory syncytial virus A2search 96% 391 96%
E NUCLEOPROTEIN P03418 (1-391) (NCAP_HRSVA)search Human respiratory syncytial virus A2search 96% 391 96%
F NUCLEOPROTEIN P03418 (1-391) (NCAP_HRSVA)search Human respiratory syncytial virus A2search 96% 391 96%
G NUCLEOPROTEIN P03418 (1-391) (NCAP_HRSVA)search Human respiratory syncytial virus A2search 96% 391 96%
H NUCLEOPROTEIN P03418 (1-391) (NCAP_HRSVA)search Human respiratory syncytial virus A2search 96% 391 96%
I NUCLEOPROTEIN P03418 (1-391) (NCAP_HRSVA)search Human respiratory syncytial virus A2search 96% 391 96%
J NUCLEOPROTEIN P03418 (1-391) (NCAP_HRSVA)search Human respiratory syncytial virus A2search 96% 391 96%
K NUCLEOPROTEIN P03418 (1-391) (NCAP_HRSVA)search Human respiratory syncytial virus A2search 96% 391 96%
L NUCLEOPROTEIN P03418 (1-391) (NCAP_HRSVA)search Human respiratory syncytial virus A2search 96% 391 96%
M NUCLEOPROTEIN P03418 (1-391) (NCAP_HRSVA)search Human respiratory syncytial virus A2search 96% 391 96%
N NUCLEOPROTEIN P03418 (1-391) (NCAP_HRSVA)search Human respiratory syncytial virus A2search 96% 391 96%
O NUCLEOPROTEIN P03418 (1-391) (NCAP_HRSVA)search Human respiratory syncytial virus A2search 96% 391 96%
P NUCLEOPROTEIN P03418 (1-391) (NCAP_HRSVA)search Human respiratory syncytial virus A2search 96% 391 96%
Q NUCLEOPROTEIN P03418 (1-391) (NCAP_HRSVA)search Human respiratory syncytial virus A2search 96% 391 96%
R NUCLEOPROTEIN P03418 (1-391) (NCAP_HRSVA)search Human respiratory syncytial virus A2search 96% 391 96%
S NUCLEOPROTEIN P03418 (1-391) (NCAP_HRSVA)search Human respiratory syncytial virus A2search 96% 391 96%
T NUCLEOPROTEIN P03418 (1-391) (NCAP_HRSVA)search Human respiratory syncytial virus A2search 96% 391 96%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P03418 (1 - 391) NUCLEOPROTEIN Human respiratory syncytial virus A strain Long

Chain Sequence family (Pfam)
A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T (P03418) PF03246: Pneumovirus nucleocapsid proteinsearch

Chain ID Molecular function (GO) Cellular component (GO) Biological process (GO)
A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T (P03418) RNA bindingsearch protein bindingsearch viral nucleocapsidsearch viral capsidsearch helical viral capsidsearch host cell cytoplasmsearch virionsearch suppression by virus of host type I interferon-mediated signaling pathwaysearch suppression by virus of host innate immune responsesearch viral processsearch suppression by virus of host PKR activitysearch evasion or tolerance by virus of host immune responsesearch

Chain InterPro annotation
A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T Pneumovirus nucleocapsid proteinsearch