› 2wiv

X-ray diffraction
1.9Å resolution

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-184552 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Flavodoxin-like domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 394 amino acids
Theoretical weight: 43.63 KDa
Source organism: Rhodococcus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8GPH7 (Residues: 159-552; Coverage: 71%)
Gene name: xplA
Sequence domains: Cytochrome P450
Structure domains: Cytochrome P450

Ligands and Environments

1 bound ligand:
Ligand HEM 2 x HEM
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: P21
Unit cell:
a: 54.129Å b: 123.019Å c: 64.608Å
α: 90° β: 98.54° γ: 90°
R-values:
R R work R free
0.169 0.167 0.214
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Conformational plasticity and structure/function relationships in cytochromes P450.
Pochapsky et al. (2010)
3 more

1 mention without citation

The 1.5-A structure of XplA-heme, an unusual cytochrome P450 heme domain that catalyzes reductive biotransformation of royal demolition explosive.
Sabbadin et al. (2009)