HUMAN C-MET KINASE IN COMPLEX WITH AZAINDOLE INHIBITOR
The structure was published by Porter, J., Lumb, S., Franklin, R.J., et al., Reuberson, J., Meier, C., and Batchelor, M., in 2009 in a paper entitled "Discovery of 4-Azaindoles as Novel Inhibitors of C- met Kinase." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.0 Å and deposited in 2009.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of HEPATOCYTE GROWTH FACTOR RECEPTOR. This molecule has the UniProt identifier P08581 (MET_HUMAN). The sample contained 292 residues which is < 90% of the natural sequence. Out of 292 residues 288 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: