CRYSTAL STRUCTURE OF HUMAN JNK3 COMPLEXED WITH A 1-ARYL-3,4-DIHYDROISOQUINOLINE INHIBITOR
The structure was published by Christopher, J.A., Atkinson, F.L., Bax, B.D., et al., Jones, E.J., Mosley, J.E., and Musgrave, J.R., in 2009 in a paper entitled "1-Aryl-3,4-Dihydroisoquinoline Inhibitors of Jnk3." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.4 Å and deposited in 2009.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of MITOGEN-ACTIVATED PROTEIN KINASE 10. This molecule has the UniProt identifier P53779 (MK10_HUMAN). The sample contained 364 residues which is < 90% of the natural sequence. Out of 364 residues 346 were observed and are deposited in the PDB.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: