2w9l

X-ray diffraction
2.91Å resolution

CANINE ADENOVIRUS TYPE 2 FIBRE HEAD IN COMPLEX WITH CAR DOMAIN D1 AND SIALIC ACID

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
PDBe Complex ID:
PDB-CPX-160224 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (4 distinct):
Coxsackievirus and adenovirus receptor Chains: A, B, G, J, K, O, P, T, V, X, Y, Z
Molecule details ›
Chains: A, B, G, J, K, O, P, T, V, X, Y, Z
Length: 124 amino acids
Theoretical weight: 13.8 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P78310 (Residues: 16-139; Coverage: 35%)
Gene names: CAR, CXADR
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins
Fiber protein Chains: C, D, E, F, H, I, L, M, N, Q, R, S
Molecule details ›
Chains: C, D, E, F, H, I, L, M, N, Q, R, S
Length: 197 amino acids
Theoretical weight: 21.69 KDa
Source organism: Canine adenovirus 2
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q65914 (Residues: 357-542; Coverage: 34%)
Gene name: L5
Structure domains: Adenovirus pIV-related, attachment domain

Ligands and Environments

Carbohydrate polymer : NEW Components: GAL, SIA
Carbohydrate polymer : NEW Components: SIA, GL0
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: I422
Unit cell:
a: 221.15Å b: 221.15Å c: 391.6Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.197 0.197 0.254
Expression system: Escherichia coli BL21