› 2w75

X-ray diffraction
2.9Å resolution

Structures of P. aeruginosa FpvA bound to heterologous pyoverdines: Apo-FpvA

Released:
DOI: 10.2210/pdb2w75/pdb
PDB entry 2w75 coloured by chain, front view.
PDB entry 2w75 coloured by chain, side view.
PDB entry 2w75 coloured by chain, top view.
Source organism: Pseudomonas aeruginosa PAO1
Primary publication:
FpvA bound to non-cognate pyoverdines: molecular basis of siderophore recognition by an iron transporter.
Greenwald J, Nader M, Celia H, Gruffaz C, Geoffroy V, Meyer JM, Schalk IJ, Pattus F
Mol Microbiol 72 1246-59 (2009)
PMID: 19504741

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-155773 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ferripyoverdine receptor Chains: A, B
Molecule details ›
Chains: A, B
Length: 772 amino acids
Theoretical weight: 86.56 KDa
Source organism: Pseudomonas aeruginosa PAO1
Expression system: Pseudomonas aeruginosa
UniProt:
  • Canonical: P48632 (Residues: 44-815; Coverage: 100%)
Gene names: PA2398, fpvA
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand N8E 2 x N8E
Ligand PO4 10 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE BW7B
Spacegroup: C2
Unit cell:
a: 193.794Å b: 129.526Å c: 140.952Å
α: 90° β: 130.57° γ: 90°
R-values:
R R work R free
0.214 0.212 0.254
Expression system: Pseudomonas aeruginosa

Quick links

Citations

12 review citations

Microbial iron acquisition: marine and terrestrial siderophores.
Sandy et al. (2009)
11 more

3 mentions without citation

TonB-dependent transporters: regulation, structure, and function.
Noinaj et al. (2010)
2 more