2w68 Summary

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ENHANCING THE RECEPTOR AFFINITY OF THE SIALIC ACID-BINDING DOMAIN OF VIBRIO CHOLERAE SIALIDASE THROUGH MULTIVALENCY

The structure was published by Connaris, H., Crocker, P.R., and Taylor, G.L., in 2009 in a paper entitled "Enhancing the Receptor Affinity of the Sialic Acid-Binding Domain of Vibrio Cholerae Sialidase Through Multivalency" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.5 Å and deposited in 2008.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of SIALIDASE.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A SIALIDASE P0C6E9 (25-216) (NANH_VIBCH)search Vibrio cholerae O1 biovar El Tor str. N16961search 100% 195 100%
B SIALIDASE P0C6E9 (25-216) (NANH_VIBCH)search Vibrio cholerae O1 biovar El Tor str. N16961search 100% 195 100%
C SIALIDASE P0C6E9 (25-216) (NANH_VIBCH)search Vibrio cholerae O1 biovar El Tor str. N16961search 100% 195 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P0C6E9 (25 - 216) SIALIDASE Vibrio cholerae

Chain Structural classification (CATH) Sequence family (Pfam)
A, B, C (P0C6E9) Jelly Rollssearch PF09264: Vibrio cholerae sialidase, lectin insertionsearch

Chain ID Molecular function (GO)
A, B, C (P0C6E9) sialic acid bindingsearch

Chain InterPro annotation
A, B, C search Concanavalin A-like lectin/glucanase domainsearch Vibrio cholerae neuraminidase, lectin-like domainsearch