2w1z Summary

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ROP2 FROM TOXOPLASMA GONDII: A VIRULENCE FACTOR WITH A PROTEIN-KINASE FOLD AND NO ENZYMATIC ACTIVITY.

The structure was published by Labesse, G., Gelin, M., Bessin, Y., et al., Cerdan, R., Arold, S.T., and Dubremetz, J.-F., in 2009 in a paper entitled "Rop2 from Toxoplasma Gondii: A Virulence Factor with a Protein-Kinase Fold and No Enzymatic Activity." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.97 Å and deposited in 2008.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of ROP2.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A ROP2 Q27007 (195-561) (Q27007_TOXGO)search Toxoplasma gondiisearch < 90% 368 97%
B ROP2 Q27007 (195-561) (Q27007_TOXGO)search Toxoplasma gondiisearch < 90% 368 97%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q27007 (195 - 561) ROP2 Toxoplasma gondii RH

Chain Structural classification (CATH) Sequence family (Pfam)
A, B Transferase(Phosphotransferase) domain 1search, Phosphorylase Kinase; domain 1search Kinase-likesearch

Chain ID Biological process (GO) Molecular function (GO)
A, B (Q27007) protein phosphorylationsearch transferase activity, transferring phosphorus-containing groupssearch protein kinase activitysearch ATP bindingsearch

Chain InterPro annotation
A, B Protein kinase domainsearch Protein kinase-like domainsearch Protein kinase-like domain, Apicomplexasearch