STRUCTURE DETERMINATION OF AURORA KINASE IN COMPLEX WITH INHIBITOR
The structure was published by Howard, S., Berdini, V., Boulstridge, J.A., et al., Williams, G., Vinkovic, M., and Wyatt, P.G., in 2009 in a paper entitled "Fragment-Based Discovery of the Pyrazol-4-Yl Urea (at9283), a Multitargeted Kinase Inhibitor with Potent Aurora Kinase Activity." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.93 Å and deposited in 2008.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of SERINE/THREONINE-PROTEIN KINASE 6.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: