STRUCTURE OF THE P53 CORE DOMAIN MUTANT Y220C BOUND TO THE STABILIZING SMALL-MOLECULE DRUG PHIKAN083
The structure was published by Boeckler, F.M., Joerger, A.C., Jaggi, G., Rutherford, T.J., Veprintsev, D.B., and Fersht, A.R., in 2008 in a paper entitled "Targeted Rescue of a Destabilized Mutant of P53 by an in Silico Screened Drug." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 1.5 Å and deposited in 2008.
The experimental data on which the structure is based was also deposited.
This PDB entry contains multiple copies of the structure of CELLULAR TUMOR ANTIGEN P53.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: