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PDB entry 2vt4

TURKEY BETA1 ADRENERGIC RECEPTOR WITH STABILISING MUTATIONS AND BOUND CYANOPINDOLOL

The structure was published by Warne, A., Serrano-Vega, M.J., Baker, J.G., et al., Leslie, A.G.W., Tate, C.G., and Schertler, G.F.X., in 2008 in a paper entitled "Structure of the Beta1-Adrenergic G Protein-Coupled Receptor" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.7 Å and deposited in 2008.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of BETA1 ADRENERGIC RECEPTOR.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A BETA1 ADRENERGIC RECEPTOR P07700 (33-367) (ADRB1_MELGA)search Meleagris gallopavosearch < 90% 313 88%
B BETA1 ADRENERGIC RECEPTOR P07700 (33-367) (ADRB1_MELGA)search Meleagris gallopavosearch < 90% 313 88%
C BETA1 ADRENERGIC RECEPTOR P07700 (33-367) (ADRB1_MELGA)search Meleagris gallopavosearch < 90% 313 88%
D BETA1 ADRENERGIC RECEPTOR P07700 (33-367) (ADRB1_MELGA)search Meleagris gallopavosearch < 90% 313 88%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P07700 (33 - 367) BETA1 ADRENERGIC RECEPTOR Meleagris gallopavo

Chain Structural classification (CATH) Sequence family (Pfam)
A, B, C, D Rhopdopsin 7-helix transmembrane proteinssearch 7 transmembrane receptor (rhodopsin family)search

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A, B, C, D Adrenergic receptor activitysearch Adrenergic receptor signaling pathwaysearch, G-protein coupled receptor signaling pathwaysearch Integral to membranesearch

Chain InterPro annotation
A, B, C, D GPCR, rhodopsin-like, 7TMsearch, Adrenergic receptor, beta 1search, Adrenergic receptorsearch, GPCR, rhodopsin-like superfamilysearch