› 2vrn

X-ray diffraction
2.15Å resolution

The structure of the stress response protein DR1199 from Deinococcus radiodurans: a member of the DJ-1 superfamily

Released:
DOI: 10.2210/pdb2vrn/pdb
PDB entry 2vrn coloured by chain, front view.
PDB entry 2vrn coloured by chain, side view.
PDB entry 2vrn coloured by chain, top view.
Source organism: Deinococcus radiodurans R1
Primary publication:
Structure of the stress response protein DR1199 from Deinococcus radiodurans: a member of the DJ-1 superfamily.
Fioravanti E, Durá MA, Lascoux D, Micossi E, Franzetti B, McSweeney S
Biochemistry 47 11581-9 (2008)
PMID: 18850720

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193291 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DJ-1/PfpI domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 190 amino acids
Theoretical weight: 20.7 KDa
Source organism: Deinococcus radiodurans R1
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9RV31 (Residues: 1-190; Coverage: 100%)
Gene name: DR_1199
Sequence domains: DJ-1/PfpI family
Structure domains: Rossmann fold

Ligands and Environments

1 bound ligand:
Ligand MG 1 x MG
1 modified residue:
Ligand CSO 2 x CSO

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: P21212
Unit cell:
a: 65.838Å b: 88.562Å c: 64.088Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.203 0.2 0.261
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

4 review citations

DJ-1 and prevention of oxidative stress in Parkinson's disease and other age-related disorders.
Kahle et al. (2009)
3 more

3 mentions without citation

Chemical approaches to detect and analyze protein sulfenic acids.
Furdui et al. (2014)
2 more