STRUCTURE OF HDAC4 CATALYTIC DOMAIN BOUND TO A TRIFLUOROMETHYLKETONE INHBITOR
The structure was published by Bottomley, M.J., Lo Surdo, P., Di Giovine, P., et al., Steinkuhler, C., Gallinari, P., and Carfi, A., in 2008 in a paper entitled "Structural and Functional Analysis of the Human Hdac4 Catalytic Domain Reveals a Regulatory Zinc-Binding Domain." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.1 Å and deposited in 2008.
The experimental data on which the structure is based was also deposited.
The PDB entry contains the structure of HISTONE DEACETYLASE 4.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule is most likely monomeric.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 1 unique UniProt protein: