Function and Biology Details
Reaction catalysed:
L-alanine + H(2)O + NAD(+) = pyruvate + NH(3) + NADH
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain
- Alanine dehydrogenase
- Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2
- NAD(P)-binding domain superfamily
- Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1
- Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal
Structure analysis Details
Assembly composition:
homo hexamer (preferred)
Assembly name:
Alanine dehydrogenase (preferred)
PDBe Complex ID:
PDB-CPX-162061 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alanine dehydrogenase
Molecule details ›
Chains: A, B, C, D, E, F
Length: 377 amino acids
Theoretical weight: 39.58 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Structure domains: NAD(P)-binding Rossmann-like Domain
Length: 377 amino acids
Theoretical weight: 39.58 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P9WQB1 (Residues: 1-371; Coverage: 100%)
Sequence domains:
Structure domains: NAD(P)-binding Rossmann-like Domain
