CRYSTAL STRUCTURE OF AURORA B KINASE IN COMPLEX WITH A AMINOTHIAZOLE INHIBITOR
The structure was published by Andersen, C.B., Wan, Y., Chang, J.W., et al., Heald, R., Musacchio, A., and Gray, N.S., in 2008 in a paper entitled "Discovery of Selective Aminothiazole Aurora Kinase Inhibitors" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 1.7 Å and deposited in 2007.
The experimental data on which the structure is based was also deposited.
This PDB entry contains a complex of 2 biomacromolecules, namely SERINE/THREONINE-PROTEIN KINASE 12-A and INNER CENTROMERE PROTEIN A.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 2 unique UniProt proteins: