2vdv Summary



The structure was published by Leulliot, N., Chaillet, M., Durand, D., Ulryck, N., Blondeau, K., and Van Tilbeurgh, H., in 2008 in a paper entitled "Structure of the Yeast tRNA M7G Methylation Complex." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.3 Å and deposited in 2007.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
E TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE Q12009 (47-286) (TRMB_YEAST)search Saccharomyces cerevisiae S288csearch < 90% 246 87%
F TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE Q12009 (47-286) (TRMB_YEAST)search Saccharomyces cerevisiae S288csearch < 90% 246 87%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q12009 (47 - 286) TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE Saccharomyces cerevisiae

Chain Sequence family (Pfam)
E, F Putative methyltransferasesearch

Chain ID Molecular function (GO) Biological process (GO)
E, F (Q12009) tRNA (guanine-N7-)-methyltransferase activitysearch tRNA modificationsearch

Chain InterPro annotation
E, F tRNA (guanine-N-7) methyltransferasesearch tRNA (guanine-N-7) methyltransferase catalytic subunit Trm8, eukaryotesearch S-adenosyl-L-methionine-dependent methyltransferase-likesearch