2vda Summary

pdbe.org/2vda
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SOLUTION STRUCTURE OF THE SECA-SIGNAL PEPTIDE COMPLEX

The structure was published by Gelis, I., Bonvin, A.M.J.J., Keramisanou, D., et al., Karamanou, S., Economou, A., and Kalodimos, C.G., in 2007 in a paper entitled "Structural Basis for Signal-Sequence Recognition by the Translocase Motor Seca as Determined by NMR" (abstract).

The structure was determined using NMR spectroscopy and deposited in 2007.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely TRANSLOCASE SUBUNIT SECA and MALTOPORIN.

The molecule most likely forms heterodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A TRANSLOCASE SUBUNIT SECA P10408 (9-836) (SECA_ECOLI)search Escherichia coli K-12search 92% 828 100%
B MALTOPORIN Q8CVI4 (1-3) (LAMB_ECOL6)search ,
Q8CVI4 (8-25) (LAMB_ECOL6)search
Escherichia coli CFT073search ,
Escherichia coli CFT073search
< 90% ,
< 90%
28 100%


This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
P10408 (9 - 836) TRANSLOCASE SUBUNIT SECA Escherichia coli
Q8CVI4 (1 - 3) MALTOPORIN ESCHERICHIA COLI

Chain Sequence family (Pfam)
A (P10408) PF07516: SecA Wing and Scaffold domainsearch, PF07517: SecA DEAD-like domainsearch
B

Chain ID Biological process (GO) Cellular component (GO) Molecular function (GO)
A (P10408) protein importsearch intracellular protein transportsearch protein targetingsearch chaperone-mediated protein foldingsearch protein transport by the Sec complexsearch intracellular protein transmembrane transportsearch transportsearch protein transportsearch membranesearch cell envelope Sec protein transport complexsearch integral component of plasma membranesearch plasma membranesearch cytosolsearch cytoplasmsearch identical protein bindingsearch metal ion bindingsearch protein bindingsearch nucleotide bindingsearch ATP bindingsearch protein-transmembrane transporting ATPase activitysearch

Chain InterPro annotation
A Protein translocase subunit SecAsearch SecA DEAD-like, N-terminalsearch SecA Wing/Scaffoldsearch SecA preprotein, cross-linking domainsearch SecA motor DEADsearch SecA conserved sitesearch P-loop containing nucleoside triphosphate hydrolasesearch
B