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PDBe Entry: 2v8x 
CRYSTALLOGRAPHIC AND MASS SPECTROMETRIC CHARACTERISATION OF EIF4E WITH N7-CAP DERIVATIVES
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TRANSLATION
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X-RAY DIFFRACTION
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Resolution: 2.3 Å, R-factor: 19.2%, Free R-factor: 25.9%, Spacegroup: P 21 21 21
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28/08/2007, deposition: 16/08/2007, last revision: 24/02/2009
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Brown, C.J.; Mcnae, I.; Fischer, P.M.; Walkinshaw, M.D.
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Crystallographic and Mass Spectrometric Characterisation of Eif4E with N(7)-Alkylated CAP Derivatives.
J.MOL.BIOL. vol:372, pag:7 (2007) [PubMed ID 17631896 ]
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TRANSLATION, PHOSPHORYLATION, INITIATION FACTOR, CAP, EIF4E, 7BNGMP, 4E-BP1, RNA-BINDING, ACETYLATION, HOST-VIRUS INTERACTION, PROTEIN SYNTHESIS INHIBITOR, PROTEIN BIOSYNTHESIS, TRANSLATION REGULATION
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Homo sapiens(human) 9606(A E)
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Eukaryotic translation initiation factor 4E (eIF-4E) (eIF4E) (mRNA cap-binding protein) (eIF-4F 25 kDa subunit) P06730 (A E)
Eukaryotic translation initiation factor 4E-binding protein 1 (eIF4E-binding protein 1) (4E-BP1) (Phosphorylated heat- and acid-stable protein regulated by insulin 1) (PHAS-I) Q13541 (B F)
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A, B, E, F
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1ipb, 2v8w, 1ipc, 2jgc, 2jgb, 2v8y
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| A, E |
EUKARYOTIC TRANSLATION INITIATION FACTOR 4E |
Protein |
P06730 (IF4E_HUMAN)
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217 |
83% |
| B, F |
EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN 1 |
Protein |
Q13541 (4EBP1_HUMAN)
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14 |
100% |
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| A, E |
7-BENZYL GUANINE MONOPHOSPHATE |
MGQ
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