spacer
EBI PDBe PDBeView

PDBe Entry: 2v6m view

CRYSTAL STRUCTURE OF LACTATE DEHYDROGENASE FROM THERMUS THERMOPHILUS HB8 (APO FORM)
Summary
Header OXIDOREDUCTASEsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 2.2 Å, R-factor: 19.6%, Free R-factor: 21.8%, Spacegroup: P 1 21 1
Released 25/09/2007, deposition: 19/07/2007, last revision: 24/02/2009
Authors Coquelle, N.search; Fioravanti, E.search; Weik, M.search; Vellieux, F.search
Primary citation Activity, Stability and Structural Studies of Lactate Dehydrogenases Adapted to Extreme Thermal Environments.
J.MOL.BIOL.search vol:374, pag:547 (2007) [PubMed ID 17936781 ]search
Keywords OXIDOREDUCTASEsearch, PHOSPHORYLATIONsearch, NADsearch, LACTATEsearch, CYTOPLASMsearch, GLYCOLYSISsearch, THERMOPHILEsearch
EC 1.1.1.27 ExPASy BRENDA search (A B C D)
Organism Thermus thermophilus HB8 300852search(A B C D)
UniProt L-lactate dehydrogenase (EC 1.1.1.27) (L-LDH) Q5SJA1search (A B C D)
Solvent A, B, C, D
Related entries 2v7p
Polymers
Id Name Type UniProt Residues Observed
A, B, C, D L-LACTATE DEHYDROGENASE Protein Q5SJA1 (LDH_THET8)search
 310 100%
Heterogens
Id Name Ligands
B, C, D 2-(N-MORPHOLINO)-ETHANESULFONIC ACID MES search
spacer