› 2v6c

X-ray diffraction
2.5Å resolution

Crystal structure of ErbB3 binding protein 1 (Ebp1)

Released:
DOI: 10.2210/pdb2v6c/pdb
PDB entry 2v6c coloured by chain, front view.
PDB entry 2v6c coloured by chain, side view.
PDB entry 2v6c coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Structural insights into the transcriptional and translational roles of Ebp1.
Monie TP, Perrin AJ, Birtley JR, Sweeney TR, Karakasiliotis I, Chaudhry Y, Roberts LO, Matthews S, Goodfellow IG, Curry S
EMBO J 26 3936-44 (2007)
PMID: 17690690

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156227 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Proliferation-associated protein 2G4 Chain: A
Molecule details ›
Chain: A
Length: 353 amino acids
Theoretical weight: 39.39 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P50580 (Residues: 8-360; Coverage: 90%)
Gene names: Ebp1, Pa2g4, Plfap
Sequence domains: Metallopeptidase family M24
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X11
Spacegroup: P212121
Unit cell:
a: 49.147Å b: 72.779Å c: 115.624Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.182 0.182 0.213
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

23 review citations

Cellular responses to auxin: division versus expansion.
Perrot-Rechenmann C. (2010)
22 more

3 mentions without citation

A structural view of PA2G4 isoforms with opposing functions in cancer.
Stevenson et al. (2020)
2 more