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PDBe Entry: 2v3f 
ACID-BETA-GLUCOSIDASE PRODUCED IN CARROT
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HYDROLASE
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X-RAY DIFFRACTION
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Resolution: 1.95 Å, R-factor: 15.4%, Free R-factor: 19.6%, Spacegroup: P 1 21 1
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08/04/2008, deposition: 17/06/2007, last revision: 24/02/2009
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Shaaltiel, Y.; Bartfeld, D.; Hashmueli, S.; Baum, G.; Brill-Almon, E.; Galili, G.; Dym, O.; Boldin-Adamsky, S.A.; Silman, I.; Sussman, J.L.; Futerman, A.H.; Aviezer, D.; Center(Ispc), Israel Structural Proteomics
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Production of Glucocerebrosidase with Terminal Mannose Glycans for Enzyme Replacement Therapy of Gaucher'S Disease Using a Plant Cell System.
PLANT BIOTECHNOL. J. vol:5, pag:579-590 (2007) [PubMed ID 17524049 ]
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ALTERNATIVE INITIATION, SPHINGOLIPID METABOLISM, GAUCHER DISEASE, DISEASE MUTATION, LIPID METABOLISM, POLYMORPHISM, GLYCOPROTEIN, PHARMACEUTICAL, N-BUTYL-DEOXYNOJIRIMYCIN, ALTERNATIVE SPLICING, ACID-BETA-GLUCOSIDASE, MEMBRANE, LYSOSOME, HYDROLASE, GLYCOSIDASE
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3.2.1.45 ExPASy BRENDA (A B)
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Homo sapiens(human) 9606(A B)
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Glucosylceramidase precursor (EC 3.2.1.45) (Beta-glucocerebrosidase) (Acid beta-glucosidase) (D-glucosyl-N-acylsphingosine glucohydrolase) (Alglucerase) (Imiglucerase) P04062 (A B)
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A, B
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1ogs, 1y7v, 2f61, 2j25, 2v3d, 2v3e
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| A, B |
GLUCOSYLCERAMIDASE |
Protein |
P04062 (GLCM_HUMAN)
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505 |
98% |
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| A |
SUGAR (4-MER) |
NAG
MAN
FUC
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| A, B |
2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL |
BTB
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| A, B |
SULFATE ION |
SO4
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| B |
SUGAR (3-MER) |
NAG
FUC
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