STRUCTURE OF PKA-PKB CHIMERA COMPLEXED WITH 7-AZAINDOLE
The structure was published by Donald, A., Mchardy, T., Rowlands, M.G., et al., Aherne, G.W., Garrett, M.D., and Collins, I., in 2007 in a paper entitled "Rapid Evolution of 6-Phenylpurine Inhibitors of Protein Kinase B Through Structure-Based Design" (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 2.0 Å and deposited in 2007.
The experimental data on which the structure is based was also deposited.
This PDB entry contains a complex of 2 biomacromolecules, namely CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT and CAMP-DEPENDENT PROTEIN KINASE INHIBITOR ALPHA.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms heterodimers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 2 unique UniProt proteins: