2tn4 Summary

pdbe.org/2tn4
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FOUR CALCIUM TNC

The structure was published by Houdusse, A., Love, M.L., Dominguez, R., Grabarek, Z., and Cohen, C., in 1997 in a paper entitled "Structures of four Ca2+-bound troponin C at 2.0 A resolution: further insights into the Ca2+-switch in the calmodulin superfamily." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.0 Å and deposited in 1997.

The experimental data on which the structure is based was not deposited.

The PDB entry contains the structure of TROPONIN C. This molecule has the UniProt identifier P02586 (TNNC2_RABIT)search. The sample contained 159 residues which is 99% of the natural sequence. Out of 159 residues 155 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A TROPONIN C P02586 (2-160) (TNNC2_RABIT)search Oryctolagus cuniculussearch 99% 159 97%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P02586 (2 - 160) TROPONIN C Oryctolagus cuniculus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A (P02586) Calmodulin-likesearch EF-handsearch PF13499: EF-hand domain pairsearch, PF13833: EF-hand domain pairsearch

Chain ID Molecular function (GO)
A (P02586) calcium ion bindingsearch metal ion bindingsearch troponin T bindingsearch

Chain InterPro annotation
A EF-hand domainsearch EF-hand domain pairsearch EF-Hand 1, calcium-binding sitesearch