2sqc Summary

pdbe.org/2sqc
spacer

SQUALENE-HOPENE CYCLASE FROM ALICYCLOBACILLUS ACIDOCALDARIUS

The structure was published by Wendt, K.U., Lenhart, A., and Schulz, G.E., in 1999 in a paper entitled "The structure of the membrane protein squalene-hopene cyclase at 2.0 A resolution." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.0 Å and deposited in 1998.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of SQUALENE-HOPENE CYCLASE.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A SQUALENE-HOPENE CYCLASE P33247 (1-631) (SQHC_ALIAD)search Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446search 100% 631 98%
B SQUALENE-HOPENE CYCLASE P33247 (1-631) (SQHC_ALIAD)search Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446search 100% 631 98%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P33247 (1 - 631) SQUALENE-HOPENE CYCLASE Alicyclobacillus acidocaldarius

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B (P33247) Terpene synthasessearch Glycosyltransferasesearch PF00432: Prenyltransferase and squalene oxidase repeatsearch, PF13249: Prenyltransferase-likesearch

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A, B (P33247) intramolecular transferase activitysearch isomerase activitysearch squalene-hopene cyclase activitysearch lyase activitysearch hopanoid biosynthetic processsearch plasma membranesearch membranesearch

Chain InterPro annotation
A, B Terpene synthase, conserved sitesearch Hopene cyclasesearch Terpenoid cyclases/protein prenyltransferase alpha-alpha toroidsearch Squalene cyclasesearch