› 2rqt

Solution NMR

Solution structure of the human DDEF1 SH3 domain

Released:
DOI: 10.2210/pdb2rqt/pdb
PDB entry 2rqt coloured by chain, ensemble of 20 models, front view.
PDB entry 2rqt coloured by chain, ensemble of 20 models, side view.
PDB entry 2rqt coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Structural basis of the recognition of the SAMP motif of adenomatous polyposis coli by the Src-homology 3 domain.
Kaieda S, Matsui C, Mimori-Kiyosue Y, Ikegami T
Biochemistry 49 5143-53 (2010)
PMID: 20509626

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193920 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 Chain: A
Molecule details ›
Chain: A
Length: 61 amino acids
Theoretical weight: 7.07 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9ULH1 (Residues: 1069-1129; Coverage: 5%)
Gene names: ASAP1, DDEF1, KIAA1249, PAG2
Sequence domains: Variant SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics, simulated annealing
Expression system: Escherichia coli

Quick links

Citations

1 review citation

The structural biology of canonical Wnt signalling.
Agostino et al. (2020)
1 other article

4 mentions without citation

A practical implicit solvent potential for NMR structure calculation.
Tian et al. (2014)
3 more