2rq8 Summary

pdbe.org/2rq8
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Solution NMR structure of titin I27 domain mutant

The structure was published by Yagawa, K., Yamano, K., Oguro, T., et al., Momose, T., Kawano, S., and Endo, T., in 2010 in a paper entitled "Structural basis for unfolding pathway-dependent stability of proteins: Vectorial unfolding vs. global unfolding" (abstract).

The structure was determined using NMR spectroscopy and deposited in 2009.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Titin. This molecule has the UniProt identifier Q8WZ42 (TITIN_HUMAN)search. The sample contained 98 residues which is < 90% of the natural sequence. Out of 98 residues 98 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Titin Q8WZ42 (12677-12765) (TITIN_HUMAN)search Homo sapienssearch < 90% 98 100%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
Q8WZ42 (12677 - 12765) Titin Homo sapiens

Chain Structural classification (CATH)
A Immunoglobulinssearch
Chain InterPro annotation
A Immunoglobulin subtypesearch Immunoglobulin I-setsearch Immunoglobulin-like foldsearch