2rot Summary

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Structure of chimeric variant of SH3 domain- SHH

The structure was published by Kutyshenko, V.P., Prokhorov, D.A., Timchenko, M.A., et al., Khristoforov, V.S., Filimonov, V.V., and Uversky, V.N., in 2009 in a paper entitled "Solution structure and dynamics of the chimeric SH3 domains, SHH- and SHA-"Bergeracs"." (abstract).

The structure was determined using NMR spectroscopy and deposited in 2008.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Spectrin alpha chain, brain. This molecule has the UniProt identifier P07751 (SPTN1_CHICK)search. The sample contained 70 residues which is < 90% of the natural sequence. Out of 70 residues 70 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Spectrin alpha chain, brain Not available
Gallus gallussearch Not available 70 100%


Chain ID Biological process (GO)
A () endocytosissearch

Chain InterPro annotation
A SH3 domainsearch Spectrin alpha chain, SH3 domainsearch Endophilin-Asearch