› › Function and Biology

Structural Basis of PxxDY motif recognition in SH3 binding

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

Quick links

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF02189
Domain description: Immunoreceptor tyrosine-based activation motif
Occurring in:
  1. T-cell surface glycoprotein CD3 epsilon chain
The deposited structure of PDB entry 2rol contains 1 copy of Pfam domain PF02189 (Immunoreceptor tyrosine-based activation motif) in T-cell surface glycoprotein CD3 epsilon chain. Showing 1 copy in chain B.

PF00018
Domain description: SH3 domain
Occurring in:
  1. Epidermal growth factor receptor kinase substrate 8-like protein 1
The deposited structure of PDB entry 2rol contains 1 copy of Pfam domain PF00018 (SH3 domain) in Epidermal growth factor receptor kinase substrate 8-like protein 1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001452
Domain description: SH3 domain
Occurring in:
  1. Epidermal growth factor receptor kinase substrate 8-like protein 1
IPR035462
Domain description: Eps8, SH3 domain
Occurring in:
  1. Epidermal growth factor receptor kinase substrate 8-like protein 1
IPR036028
Domain description: SH3-like domain superfamily
Occurring in:
  1. Epidermal growth factor receptor kinase substrate 8-like protein 1
IPR039801
Domain description: Epidermal growth factor receptor kinase substrate 8-like
Occurring in:
  1. Epidermal growth factor receptor kinase substrate 8-like protein 1

Structure domain

CATH CATH domain
2.30.30.40
Class: Mainly Beta
Architecture: Roll
Topology: SH3 type barrels.
Homology: SH3 Domains
Occurring in:
  1. Epidermal growth factor receptor kinase substrate 8-like protein 1
The deposited structure of PDB entry 2rol contains 1 copy of CATH domain 2.30.30.40 (SH3 type barrels.) in Epidermal growth factor receptor kinase substrate 8-like protein 1. Showing 1 copy in chain A.

Quick links