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PDBe Entry: 2roc view

Solution structure of Mcl-1 Complexed with Puma
Summary
Header Apoptosissearch
Method SOLUTION NMR
Experiment
Released 08/07/2008, deposition: 17/03/2008, last revision: 24/02/2009
Authors Day, C.L.search; Smits, C.search; Fan, F.C.search; Lee, E.F.search; Fairlie, W.D.search; Hinds, M.G.search
Primary citation Structure of the BH3 Domains from the p53-Inducible BH3-Only Proteins Noxa and Puma in Complex with Mcl-1
J.MOL.BIOL.search vol:380, pag:958-971 (2008) [PubMed ID 18589438 ]search
Keywords Mcl-1search, Bcl-2search, apoptosissearch, Pumasearch, BH3-onlysearch, Cytoplasmsearch, Developmental proteinsearch, Differentiationsearch, Membranesearch, Mitochondrionsearch, Nucleussearch, Phosphoproteinsearch, Transmembranesearch, Ubl conjugationsearch
Organism Mus musculus(house mouse) 10090search(A B)
UniProt Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Bcl-2-related protein EAT/mcl1) P97287search (A)
Bcl-2-binding component 3 (p53 up-regulated modulator of apoptosis) Q99ML1search (B)
Related entries 1wsx, 2jm6, 2rod
Polymers
Id Name Type UniProt Residues Observed
A Induced myeloid leukemia cell differentiation protein Mcl-1 homolog Protein P97287 (MCL1_MOUSE)search
162 100%
B Bcl-2-binding component 3 Protein Q99ML1 (BBC3_MOUSE)search
27 100%
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