Crystal structure of the complex between the EGFR kinase domain and a Mig6 peptide
The structure was published by Zhang, X., Pickin, K.A., Bose, R., Jura, N., Cole, P.A., and Kuriyan, J., in 2007 in a paper entitled "Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 3.6 Å and deposited in 2007.
The experimental data on which the structure is based was also deposited.
This PDB entry contains a complex of 2 biomacromolecules, namely Epidermal growth factor receptor and ERBB receptor feedback inhibitor 1.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 2 unique UniProt proteins: