Structure of a human p110alpha/p85alpha complex
The structure was published by Huang, C.H., Mandelker, D., Schmidt-Kittler, O., et al., Vogelstein, B., Gabelli, S.B., and Amzel, L.M., in 2007 in a paper entitled "The structure of a human p110alpha/p85alpha complex elucidates the effects of oncogenic PI3Kalpha mutations." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 3.05 Å and deposited in 2007.
The experimental data on which the structure is based was also deposited.
This PDB entry contains a complex of 2 biomacromolecules, namely Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform and Phosphatidylinositol 3-kinase regulatory subunit alpha.
The molecule most likely forms heterodimers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 2 unique UniProt proteins: