2rc1 Summary


Cytochrome C Peroxidase W191G in complex with 2,4,5-trimethyl-3-oxazoline

The structure was published by Graves, A.P., Shivakumar, D.M., Boyce, S.E., Jacobson, M.P., Case, D.A., and Shoichet, B.K., in 2008 in a paper entitled "Rescoring docking hit lists for model cavity sites: predictions and experimental testing." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 2.49 Å and deposited in 2007.

The experimental data on which the structure is based was also deposited.

The PDB entry contains the structure of Cytochrome C Peroxidase. This molecule has the UniProt identifier P00431 (CCPR_YEAST)search. The sample contained 292 residues which is < 90% of the natural sequence. Out of 292 residues 291 were observed and are deposited in the PDB.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
X Cytochrome C Peroxidase P00431 (71-361) (CCPR_YEAST)search Saccharomyces cerevisiae S288csearch < 90% 292 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P00431 (71 - 361) Cytochrome C Peroxidase Saccharomyces cerevisiae YJM789

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
X CCP-likesearch Peroxidase; domain 1search, Peroxidase, domain 2search Peroxidasesearch

Chain ID Molecular function (GO) Biological process (GO)
X (P00431) heme bindingsearch peroxidase activitysearch response to oxidative stresssearch oxidation-reduction processsearch

Chain InterPro annotation
X Haem peroxidase, plant/fungal/bacterialsearch Plant ascorbate peroxidasesearch Haem peroxidasesearch Peroxidases heam-ligand binding sitesearch Peroxidase, active sitesearch