2r06 Summary

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PDB entry 2r06 (supersedes 1r06)

STRUCTURAL ANALYSIS OF ANTIVIRAL AGENTS THAT INTERACT WITH THE CAPSID OF HUMAN RHINOVIRUSES

The structure was published by Badger, J., Minor, I., Oliveira, M.A., Smith, T.J., and Rossmann, M.G., in 1989 in a paper entitled "Structural analysis of antiviral agents that interact with the capsid of human rhinoviruses." (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 3.0 Å and deposited in 1988.

The experimental data on which the structure is based was also deposited.

This entry contains 6 copies of 4 unique biopolymers (complete list).

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule has more than one probable quaternary state observed. For more details see the quaternary structure page.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
1 HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1) P03303 (568-856) (POLG_HRV14)search Human rhinovirus B14search < 90% 289 94%
2 HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2) P03303 (70-331) (POLG_HRV14)search Human rhinovirus B14search < 90% 262 97%
3 HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP3) P03303 (332-567) (POLG_HRV14)search Human rhinovirus B14search < 90% 236 100%
4 HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP4) P03303 (2-69) (POLG_HRV14)search Human rhinovirus B14search < 90% 68 58%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P03303 (568 - 856) HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1) Human rhinovirus B14

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
1 Picornaviridae-like VP (VP1, VP2, VP3 and VP4)search Jelly Rollssearch picornavirus capsid proteinsearch
2 Picornaviridae-like VP (VP1, VP2, VP3 and VP4)search Jelly Rollssearch picornavirus capsid proteinsearch
3 Picornaviridae-like VP (VP1, VP2, VP3 and VP4)search Jelly Rollssearch picornavirus capsid proteinsearch
4 Picornaviridae-like VP (VP1, VP2, VP3 and VP4)search Rhinovirus 14, subunit 4search Picornavirus coat protein (VP4)search

Chain ID Cellular component (GO) Molecular function (GO)
1 (P03303) viral capsidsearch structural molecule activitysearch
2 (P03303) viral capsidsearch structural molecule activitysearch
3 (P03303) viral capsidsearch structural molecule activitysearch
4 (P03303) viral capsidsearch structural molecule activitysearch

Chain InterPro annotation
1 Picornavirus capsidsearch Viral coat protein subunitsearch
2 Picornavirus capsidsearch Viral coat protein subunitsearch
3 Picornavirus capsidsearch Viral coat protein subunitsearch
4 Picornavirus coat protein VP4search