Crystal Structure of the Estrogen Receptor Alpha Ligand Binding Domain Complexed with WAY-169916
The structure was published by Bruning, J.B., Parent, A.A., Gil, G., et al., Adams, P.D., Katzenellenbogen, J.A., and Nettles, K.W., in 2010 in a paper entitled "Coupling of receptor conformation and ligand orientation determine graded activity." (abstract).
This crystal structure was determined using X-ray diffraction at a resolution of 1.72 Å and deposited in 2007.
The experimental data on which the structure is based was also deposited.
This PDB entry contains a complex of 3 biomacromolecules, namely Estrogen receptor and Nuclear receptor coactivator 2.
It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.
The molecule most likely forms heterotetramers.
The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):
This entry contains 2 unique UniProt proteins: