› 2qy7

X-ray diffraction
2Å resolution

Crystal structure of human epsinR ENTH domain

Released:
DOI: 10.2210/pdb2qy7/pdb
PDB entry 2qy7 coloured by chain, front view.
PDB entry 2qy7 coloured by chain, side view.
PDB entry 2qy7 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
A SNARE-adaptor interaction is a new mode of cargo recognition in clathrin-coated vesicles.
Miller SE, Collins BM, McCoy AJ, Robinson MS, Owen DJ
Nature 450 570-4 (2007)
PMID: 18033301

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172078 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Clathrin interactor 1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 147 amino acids
Theoretical weight: 17.43 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q14677 (Residues: 20-166; Coverage: 24%)
Gene names: CLINT1, ENTH, EPN4, EPNR, KIAA0171
Sequence domains: ENTH domain
Structure domains: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P21
Unit cell:
a: 46.455Å b: 91.122Å c: 52.893Å
α: 90° β: 107.13° γ: 90°
R-values:
R R work R free
0.206 0.204 0.255
Expression system: Escherichia coli

Quick links

Citations

26 review citations

Exiting the Golgi complex.
De Matteis et al. (2008)
25 more

2 mentions without citation

The dipeptidyl peptidase IV inhibitors vildagliptin and K-579 inhibit a phospholipase C: a case of promiscuous scaffolds in proteins.
Chakraborty et al. (2013)
1 more