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PDBe Entry: 2qwn 
Crystal structure of disulfide-bond-crosslinked complex of bovine hsc70 (1-386aa)R171C and bovine Auxilin (810-910aa)D876C in the ADP*Pi state
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CHAPERONE
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X-RAY DIFFRACTION
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Resolution: 2.4 Å, R-factor: 21.2%, Free R-factor: 27.9%, Spacegroup: P 21 21 21
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18/12/2007, deposition: 10/08/2007, last revision: 24/02/2009
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Jiang, J.; Maes, E.G.; Wang, L.; Taylor, A.B.; Hinck, A.P.; Lafer, E.M.; Sousa, R.
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Structural basis of J cochaperone binding and regulation of Hsp70.
MOL.CELL vol:28, pag:422-433 (2007) [PubMed ID 17996706 ]
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chaperone-cochaperone complex, ATP-binding, Cytoplasm, Nucleotide-binding, Nucleus, Phosphorylation, Stress response, Hydrolase, Protein phosphatase, SH3-binding
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3.1.3.48 ExPASy BRENDA (B)
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Bos taurus(cattle) 9913(A B)
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Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8) P19120 (A)
Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6) Q27974 (B)
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A, B
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2qwl, 2qwm, 2qwo, 2qwp, 2qwq, 2qwr
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| A |
Heat shock cognate 71 kDa protein |
Protein |
P19120 (HSP7C_BOVIN)
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394 |
97% |
| B |
Putative tyrosine-protein phosphatase auxilin |
Protein |
Q27974 (AUXI_BOVIN)
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94 |
100% |
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| A |
PHOSPHATE ION |
PO4
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| A |
SODIUM ION |
NA
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| A |
MAGNESIUM ION |
MG
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| A |
ADENOSINE-5'-DIPHOSPHATE |
ADP
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