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EBI PDBe PDBeView

PDBe Entry: 2quu view

Dihydroxyacetone phosphate Schiff base intermediate in mutant fructose-1,6-bisphosphate aldolase from rabbit muscle
Summary
Header LYASEsearch
Method X-RAY DIFFRACTION
Experiment Resolution: 1.98 Å, R-factor: 15.7%, Free R-factor: 19.5%, Spacegroup: P 1 21 1
Released 28/08/2007, deposition: 06/08/2007, last revision: 24/02/2009
Authors St-Jean, M.search; Sygusch, J.search
Primary citation Stereospecific proton transfer by a mobile catalyst in mammalian fructose-1,6-bisphosphate aldolase
J.BIOL.CHEM.search vol:282, pag:31028-31037 (2007) [PubMed ID 17728250 ]search
Keywords aldolasesearch, mutantsearch, substratesearch, Schiff basesearch, protonated iminesearch, intermediatesearch, covalentsearch, Acetylationsearch, Glycolysissearch, Lyasesearch, Phosphorylationsearch
EC 4.1.2.13 ExPASy BRENDA search (A B C D)
Organism Oryctolagus cuniculus(rabbit) 9986search(A B C D)
UniProt Fructose-bisphosphate aldolase A (EC 4.1.2.13) (Muscle-type aldolase) P00883search (A B C D)
Solvent A, B, C, D
Related entries 1zah, 2qut, 2quv
Polymers
Id Name Type UniProt Residues Observed
A, B, C, D Fructose-bisphosphate aldolase A Protein P00883 (ALDOA_RABIT)search
 363 100%
Heterogens
Id Name Ligands
A, B, C, D 1,3-DIHYDROXYACETONEPHOSPHATE 13P search
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