2qut Summary

pdbe.org/2qut
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Dihydroxyacetone phosphate enamine intermediate in fructose-1,6-bisphosphate aldolase from rabbit muscle

The structure was published by St-Jean, M. and Sygusch, J., in 2007 in a paper entitled "Stereospecific proton transfer by a mobile catalyst in mammalian fructose-1,6-bisphosphate aldolase" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 1.88 Å and deposited in 2007.

The experimental data on which the structure is based was also deposited.

This PDB entry contains multiple copies of the structure of Fructose-bisphosphate aldolase A.

It also contains one or more heterogenic compounds (e.g., ligands, co-factors, ions, modified amino acids, etc.); see here for a complete list.

The molecule most likely forms homotetramers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):


Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Fructose-bisphosphate aldolase A P00883 (2-364) (ALDOA_RABIT)search Oryctolagus cuniculussearch 93% 363 99%
B Fructose-bisphosphate aldolase A P00883 (2-364) (ALDOA_RABIT)search Oryctolagus cuniculussearch 93% 363 99%
C Fructose-bisphosphate aldolase A P00883 (2-364) (ALDOA_RABIT)search Oryctolagus cuniculussearch 93% 363 99%
D Fructose-bisphosphate aldolase A P00883 (2-364) (ALDOA_RABIT)search Oryctolagus cuniculussearch 93% 363 99%


This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P00883 (2 - 364) Fructose-bisphosphate aldolase A Oryctolagus cuniculus

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A, B, C, D (P00883) Class I aldolasesearch Aldolase class Isearch PF00274: Fructose-bisphosphate aldolase class-Isearch

Chain ID Molecular function (GO) Biological process (GO) Cellular component (GO)
A, B, C, D (P00883) fructose-bisphosphate aldolase activitysearch catalytic activitysearch lyase activitysearch protein bindingsearch protein homotetramerizationsearch glycolytic processsearch cytoplasmsearch M bandsearch I bandsearch

Chain InterPro annotation
A, B, C, D Fructose-bisphosphate aldolase, class-Isearch Aldolase-type TIM barrelsearch Fructose-bisphosphate aldolase class-I active sitesearch Fructose-bisphosphate aldolase class-I, eukaryotic-typesearch