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PDBe Entry: 2quj 
Crystal structures of human tryptophanyl-tRNA synthetase in complex with TrpAMP
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LIGASE
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X-RAY DIFFRACTION
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Resolution: 2.42 Å, R-factor: 21.4%, Free R-factor: 23.8%, Spacegroup: P 43 21 2
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29/04/2008, deposition: 05/08/2007, last revision: 24/02/2009
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Shen, N.; Ding, J.P.
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Catalytic mechanism of the tryptophan activation reaction revealed by crystal structures of human tryptophanyl-tRNA synthetase in different enzymatic states
NUCLEIC ACIDS RES. vol:36, pag:1288-1299 (2008) [PubMed ID 18180246 ]
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aminoacyl-tRNA synthetase, Rossmann fold, induced-fit mechnism, ATP-binding, Cytoplasm, Ligase, Nucleotide-binding, Protein biosynthesis
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6.1.1.2 ExPASy BRENDA (A B)
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Homo sapiens(human) 9606(A B)
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Tryptophanyl-tRNA synthetase, cytoplasmic (EC 6.1.1.2) (Tryptophan--tRNA ligase) (TrpRS) (Interferon-induced protein 53) (IFP53) (hWRS) P23381 (A B)
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A, B
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1o5t, 2ake
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| A, B |
Tryptophanyl-tRNA synthetase |
Protein |
P23381 (SYWC_HUMAN)
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477 |
81% |
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| A, B |
CHLORIDE ION |
CL
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| A |
TRYPTOPHANYL-5'AMP |
TYM
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| B |
TRYPTOPHAN |
TRP
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| B, A |
GLYCEROL |
GOL
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