 |
PDBe Entry: 2qnz 
Crystal structure of the complex between the mycobacterium beta-ketoacyl-acyl carrier protein synthase III (FABH) and SS-(2-hydroxyethyl)-O-decyl ester carbono(dithioperoxoic) acid
 |
TRANSFERASE
|
|
X-RAY DIFFRACTION
|
|
Resolution: 2.3 Å, R-factor: 16.959%, Free R-factor: 22.236%, Spacegroup: C 2 2 21
|
|
06/05/2008, deposition: 19/07/2007, last revision: 24/02/2009
|
|
Sachdeva, S.; Musayev, F.; Alhamadsheh, M.; Scarsdale, J.N.; Wright, H.T.; Reynolds, K.A.
|
Separate Entrance and Exit Portals for Ligand Traffic in Mycobacterium tuberculosis FabH
CHEM.BIOL. vol:15, pag:402-412 (2008) [PubMed ID 18420147 ]
|
|
FATTY ACID BIOSYNTHESIS, MYOBACTERIUM TUBERCULOSIS, STRUCTURAL BASIS FOR SUBSTRATE SPECIFICITY, ENZYME INHIBITOR COMPLEX, MECHANISM BASED INHIBITOR, Acyltransferase, Cytoplasm, Lipid synthesis, Multifunctional enzyme, Transferase
|
|
2.3.1.180 ExPASy BRENDA (A B)
|
|
Mycobacterium tuberculosis 1773(A B)
|
|
3-oxoacyl-[acyl-carrier-protein] synthase 3 (EC 2.3.1.180) (3-oxoacyl-[acyl-carrier-protein] synthase III) (Beta-ketoacyl-ACP synthase III) (KAS III) (MtFabH) P0A574 (A B)
|
|
A, B
|
|
1u6s, 1hzp, 1u6e, 1hnj, 1hnk, 2qnx, 2qny, 2qo0, 2qo1
|
| A, B |
3-oxoacyl-[acyl-carrier-protein] synthase 3 |
Protein |
P0A574 (FABH_MYCTU)
|
335 |
98% |
|
| A, B |
DECYL FORMATE |
DFD
|
| A, B |
BETA-MERCAPTOETHANOL |
BME
|
|
|
