2qmv Summary


High Resolution Structure of Peroxisone Proliferation-Activated Receptor gamma and Characterisation of its Interaction with the Co-activator Transcriptional Intermediary Factor 2

A publication describing this structure is not available. The depositing authors are Hartl, R.search; Riepl, H.search; Kauschke, S.search; Kalbitzer, H.R.search; Maurer, T.search

The structure was determined using NMR spectroscopy and deposited in 2007.

The experimental data on which the structure is based was not deposited.

The PDB entry contains the structure of Peroxisome proliferator-activated receptor gamma. This molecule has the UniProt identifier P37231 (PPARG_HUMAN)search. The sample contained 270 residues which is < 90% of the natural sequence. Out of 270 residues 270 were observed and are deposited in the PDB.

The molecule is most likely monomeric.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Peroxisome proliferator-activated receptor gamma P37231 (235-504) (PPARG_HUMAN)search Homo sapienssearch < 90% 270 100%

This entry contains 1 unique UniProt protein:

UniProt accession Name Organism PDB
P37231 (235 - 504) Peroxisome proliferator-activated receptor gamma Homo sapiens

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A Nuclear receptor ligand-binding domainsearch Retinoid X Receptorsearch Ligand-binding domain of nuclear hormone receptorsearch

Chain ID Molecular function (GO) Cellular component (GO) Biological process (GO)
A (P37231) steroid hormone receptor activitysearch DNA bindingsearch sequence-specific DNA binding transcription factor activitysearch ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activitysearch nucleussearch regulation of transcription, DNA-templatedsearch steroid hormone mediated signaling pathwaysearch

Chain InterPro annotation
A Nuclear hormone receptor, ligand-binding, coresearch Steroid hormone receptorsearch Peroxisome proliferator-activated receptorsearch Nuclear hormone receptor, ligand-bindingsearch