2qkw Summary


Structural basis for activation of plant immunity by bacterial effector protein AvrPto

The structure was published by Xing, W., Zou, Y., Liu, Q., et al., Wu, J.W., Zhou, J.M., and Chai, J., in 2007 in a paper entitled "The structural basis for activation of plant immunity by bacterial effector protein AvrPto" (abstract).

This crystal structure was determined using X-ray diffraction at a resolution of 3.2 Å and deposited in 2007.

The experimental data on which the structure is based was also deposited.

This PDB entry contains a complex of 2 biomacromolecules, namely Avirulence protein and Protein kinase.

The molecule most likely forms heterodimers.

The following tables show cross-reference information to other databases (to obtain a list of all PDB entries sharing the same property or classification, click on the magnifying glass icon):

Chain Name UniProt Name of source organism % of UniProt sequence present in the sample Residues in the sample molecules % of residues observed
A Avirulence protein Q08242 (1-164) (Q08242_PSESX)search Pseudomonas syringaesearch 100% 164 61%
B Protein kinase Q40234 (1-321) (Q40234_SOLPI)search Solanum pimpinellifoliumsearch 100% 321 90%

This entry contains 2 unique UniProt proteins:

UniProt accession Name Organism PDB
Q08242 (1 - 164) Avirulence protein Pseudomonas syringae
Q40234 (1 - 321) Protein kinase Solanum pimpinellifolium

Chain Structural classification (SCOP) Structural classification (CATH) Sequence family (Pfam)
A Avirulence protein AvrPtosearch Avirulence protein AvrPtosearch Central core of the bacterial effector protein AvrPtosearch
B (Q40234) Phosphorylase Kinase; domain 1search, Transferase(Phosphotransferase) domain 1search PF07714: Protein tyrosine kinasesearch

Chain ID Molecular function (GO) Biological process (GO)
B (Q40234) protein kinase activitysearch protein bindingsearch protein serine/threonine kinase activitysearch kinase activitysearch ATP bindingsearch transferase activity, transferring phosphorus-containing groupssearch protein phosphorylationsearch phosphorylationsearch

Chain InterPro annotation
A Type III secretion system, AvrPtosearch
B Protein kinase domainsearch Serine-threonine/tyrosine-protein kinase catalytic domainsearch Serine/threonine-protein kinase, active sitesearch Protein kinase-like domainsearch Concanavalin A-like lectin/glucanase domainsearch Protein kinase, ATP binding sitesearch